A comprehensive membrane permeability database is essential for developing computational methods for cyclic peptide drug design. Although many experimental data on membrane permeability of cyclic peptides have been reported, a comprehensive database is not yet available.
Membrane permeability is an essential indicator of oral bioavailability and intracellular targeting, and the development of membrane-permeable peptides is a bottleneck in cyclic peptide drug discovery. The license agreement expires upon the termination of the user’s affiliation with the University of Missouri.įor more information, call Software Sales at, cyclic peptides have been considered breakthrough drugs because they can interact with “undruggable” targets such as intracellular protein–protein interactions.
Departmental purchases must be made using a MoCode. The software must not be copied for someone else or loaned to someone else for them to copy. The Division of Information Technology will not knowingly assist in, or permit its equipment to be used in, violation of such agreements. It is the policy of the University of Missouri to honor software license agreements and to require all users to do likewise.
Product Support: For product-related questions, contact PerkinElmer Informatics SupportĪll licenses are for one year, based on the stated license period, and must be renewed annually for the new license period. If paying with a credit card, select Personal.ĭownload Support: For download problems or questions, contact PerkinElmer Download Center Support at or call 888.715.4687. If paying with a MoCode, select Department. Login to the DoIT Service Portal with your University user ID and password, select Service Catalog, and search for ChemOffice. S&T, UMSL, UMKC customers, please contact your local IT departments. Currently Enrolled Students (for personal use).It builds on the foundations of ChemDraw Professional and adds access to a broad set of powerful scientific tools to enable scientific research. ChemOffice is a robust, scientifically-intelligent research productivity suite.
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